전체 내용설명, 대표그림 삽입

항목별 하위구조로 설명

• 3D GPS (project holder: 이현민), HiC-seq 설명

주요연구내용 설명

핵심 연구방법 (방법 개괄만 작성하고, 주요 내용 설명은 major technique에서 동영상으로 설명)

1. 3D FISH (GPS)

2. HiC-Seq

• Nuclear Lamina (Lamins) (project holder: 신건섭)

주요연구내용 설명

핵심 연구방법

1. TSA-Seq

2. Epigenomic profiling

• Lamin associated proteins (Lap2a) (project holder: 조아라)

• Chromatin Organization Factors (HP1) (project holder: 박유나)

• DNA methylation / Demethylation (Smug1) (project holder: 안미진, 김지영, 김진호)

• Histone methylation / Demethylation (KDM3B) (project holder: 안미진, 김지영, 김진호)

Useful book

• Armstrong L, Epigenetics, Garland science, 2013. [Book link]

Cell Fate Determination

Glaucoma

• Toxico-Transcriptomics (Splicing Regulation) (project holder: 김진호)

• Toxico-Epigenomics (Histones and meDNA regulation) (project holder: 김진호)

벤조피렌

코호트 RRBS (FROM, 공동연구 등)

• NGS (RNA-seq), [유튜브 링크]

• NGS (ChIP-seq)

• NGS (DNA methylation: WGBS, RRBS)

• NGS (TSA-seq) 

• NGS (HiC-seq)

• Sequencing Technique Automation

• Single Cell Sorting (manual picking, WBC sorting, 10x genomics) [유튜브 링크]

• 3D Gene Positioning System (3D-GPS) [유튜브 링크]

• Animal Model Research

-mouse

-chicken

[유튜브 링크] 209동 실험실

[유튜브 링크] 102동 실험실

Genome Browsers

• • UCSC: https://genome.ucsc.edu

  • Ensembl: https://asia.ensembl.org/index.html

  • NCBI: https://www.ncbi.nlm.nih.gov

Sequencing Data Analysis

• • Galaxy: https://usegalaxy.org

  • IGV: https://igv.org

  • Bioconductor: https://www.bioconductor.org

Public Database

• • Expression Atlas: https://www.ebi.ac.uk/gxa/home

  • GTEx: https://gtexportal.org/home

  • The Human Protein Atlas: https://www.proteinatlas.org

  • Association to Function Knowledge Portal: https://a2f.hugeamp.org

  • Harmonizome 3.0: https://maayanlab.cloud/Harmonizome/

  • MGI (Mouse Genome Informatics): https://www.informatics.jax.org/