PROFESSOR

Education

09/2006 ~ 08/2009, Ph.D. in Molecular and Cellular Biology, Dept. of Life Science, Chung-Ang University, Korea

Thesis: “Functional network of Neural Retina Leucine-zipper (NRL) in eye development”

Supervisor: Kyung-Hee Choi, Ph.D., Professor

09/2004 ~ 02/2006, M.S. in Microbiology, Dept. of Biology, Chung-Ang University, Korea

Thesis: “Tip60 represses transcriptional activity of p73 through binding with Mdm2” (Bachelor & Master Degree Coordinated Program)

Supervisor: Kyung-Hee Choi, Ph.D., Professor

03/1999 ~ 08/2004, B.S. in Biology, Dept. of Biology, Chung-Ang University, Korea

*01/2002 ~ 02/2004, Military Service (fulfilled, ROK Army)

Research Experiences

09/2023 ~ present, Professor

Department of Life Science, College of Natural Sciences, Chung-Ang University, Korea

03/2018 ~ 08/2023, Associate Professor

Department of Life Science, College of Natural Sciences, Chung-Ang University, Korea

03/2015 ~ 02/2018, Assistant Professor

Department of Life Science, College of Natural Sciences, Chung-Ang University, Korea

06/2012 ~ 02/2015, Visiting Fellow

Neurobiology-Neurodegeneration and Repair Laboratory (N-NRL), National Eye Institute (NEI), National Institutes of Health (NIH), USA

Supervisor: Anand Swaroop, Ph.D., Senior Investigator, Lab Chief

09/2010 ~ 05/2012, Research Professor

School of Biological Sciences (Brain Korea 21 program, funded by National Research Foundation (NRF)), Chung-Ang University, Korea

09/2009 ~ 08/2010, Post-doctoral Research Fellow

Dept. of Life Science (Brain Korea 21 program, funded by National Research Foundation (NRF)), Chung-Ang University, Korea

09/2006 ~ 09/2009, Research Assistant 

Dept. of Life Science, Chung-Ang University, Korea

03/2006 ~ 08/2006, Post-Master Researcher 

funded by Korea Research Foundation (KRF) for “Degradation mechanism of MDM2 by the p19ras”, Korea

09/2004 ~ 02/2006, Research Assistant

Dept. of Life Science, Chung-Ang University, Korea

Research Interests

• Retinal differentiation and degeneration mechanisms using mouse genetic models

• Photoreceptor cell fate determination among retinal cells

• Cell-type specific researches at the single cell level

• Genome-wide epigenetic regulation in the retina (Multi-Dimensional Epigenomics)

• Various genome-wide researches by using the Next-Generation Sequencing (NGS) techniques, especially, RNA-seq, DNA methylation-seq and ChIP-seq

Teaching Experiences

09/2009 ~ 05/2012, Lecturer

Subjects: Understanding of Life Science, Molecular Biology Chung-Ang University, Korea

09/2004 ~ 08/2009, Teaching Assistant, Experimental Biology

Subjects: General Biology, Biochemistry, Molecular Biology Dept. of Life Science, Chung-Ang University, Korea

Publications & Notes

Beom Jun Park, Yoo Bin Yoon, Soon Cheol Park, Geun-Seup Shin, Hee-Jin Kwak, Dong Ho Lee, Min Young Choi, Jung-Woong Kim*, Sung–Jin Cho*. Multiple toll-like receptors (TLRs) display differential bacterial and ligand specificity in the earthworm, Eisenia andrei. Journal of Invertebrate Pathology, 2023, 201, 108010, *Co-corresponding author

Mi Jin Kim, Ah‑Ra Jo, Ji‑Young Kim, Mi‑Jin An, Geun‑Seup Shin, Hyun‑Min Lee, Jinho Kim, Jinhong Park, Chul‑Hong Kim, Jung‑Woong Kim*. Comparison of the cytotoxicity of bisphenol A and its analogs on human placental BeWo cells. Molecular & Cellular Toxicology, 2023, 19, 601-611, *Corresponding author

Jun Hyung Park, Seungwoo Hong, Ok‑Hyeon Kim, Chul‑Hong Kim, Jinho Kim, Jung‑Woong Kim*, Sungguan Hong* and Hyun Jung Lee*, Polypropylene microplastics promote metastatic features in human breast cancer. 2023, 13, 6252, *Co-corresponding author

Mi‑Jin An, Hyun‑Min Lee, Chul‑Hong Kim, Geun‑Seup Shin, Ah‑Ra Jo, Ji‑Young Kim, Mi Jin Kim, Jinho Kim, Jinhong Park, Yujeong Hwangbo, Jeongkyu Kim, Jung‑Woong Kim*, c‑Jun N‑terminal kinase 1 (JNK1) phosphorylates OTX2 transcription factor that regulates early retinal development. Genes & Genomics, 2023, 45, 429-435, *Corresponding author

Wang Hee Lee, Jun Gi Rho, Yeyoung Yang, Seulbi Lee, Sohui Kweon, Hyung-Mo Kim, Juhwan Yoon, Hongseo Choi, Eunyoung Lee, Su Ha Kim, Sohee You, Yujin Song, Young Soo Oh, Hwan Kim, Hwa Seung Han, Ji Hye Han, Myeongwoo Jung, Young Hwan Park, Yang Seon Choi, Sukyoung Han, Junho Lee, Sangdun Choi, Jung-Woong Kim, Jae Hyung Park, Eun Kyung Lee, Woo Keun Song, Eunha Kim*, and Wook Kim*. Hyaluronic Acid Nanoparticles as a Topical Agent for Treating Psoriasis. ACS Nano, 2022, 16, 20057-20074

Young Eun Koh, Eui-Hwan Choi, Jung-Woong Kim*, and Keun Pil Kim* The Kleisin Subunits of Cohesin Are Involved in the Fate Determination of Embryonic Stem Cells. 2022, 45(11), 820-832, *Co-corresponding author

Beom Jun Park, Yoo Bin Yoon, Soon Cheol Park, Dong Ho Lee, Chuog Shin, Hee-Jin Kwak, Jung-Woong Kim*, Sung-Jin Cho*. Peptidoglycan recognition proteins from the earthworm, Eisenia andrei: Differential inducibility and tissue-specific expression. Developmental and Comparative Immunology, 2022, 135, 104483, *Co-corresponding author

Ke Jiang, Anupam Kumar Mondal, Yogita K. Adlakha, Jessica Gumerson, Angel Aponte, Linn Gieser1, Jung-Woong Kim, Alexis Boleda, Matthew J. Brooks Jacob Nellissery1, Donald A. Fox, Robert Balaban, Raul Covian, Anand Swaroop. Multi-omics analyses reveal early metabolic imbalance and mitochondrial stress in neonatal photoreceptors leading to cell death in Pde6brd1/rd1 mouse model of retinal degeneration. 2022, Human Molecular Genetics

Ji‑Young Kim, Geun‑Seup Shin, Chul‑Hong Kim, Mi Jin Kim, Mi‑Jin An, Hyun‑Min Lee, Jung‑Woong Kim*. The cytotoxic effects of bisphenol A alternatives in human lung fibroblast MRC5 cells. 2021, Molecular & Cellular Toxicology, 17, 267-276, *Corresponding author

Jung‑Woong Kim*, Junyeong Yi, Jinhong Park, Ji Hoon Jeong, Jinho Kim, Jihee Won, Seok Chung, Tong‑Soo Kim, Jhang Ho Pak. Transcriptomic profiling of three-dimensional cholangiocyte spheroids long term exposed to repetitive Clonorchis sinensis excretory-secretory products. 2021, Parasites & Vectors, 14, 213, *Co-first author

Ji-Young Kim, Mi-Jin An, Geun-Seup Shin, Hyun-Min Lee, Mi Jin Kim, Chul-Hong Kim, Jung-Woong Kim*. Mercury Chloride but Not Lead Acetate Causes Apoptotic Cell Death in Human Lung Fibroblast MRC5 Cells via Regulation of Cell Cycle Progression. 2021, International Journal of Molecular Science, 22, 2494, *Corresponding author

Mi Jin Kim, Jinhong Park, Jinho Kim, Ji-Young Kim, Mi-Jin An, Geun-Seup Shin, Hyun-Min Lee, Chul-Hong Kim, Jung-Woong Kim*. Transcriptome Analysis Reveals HgCl2 Induces Apoptotic Cell Death in Human Lung Carcinoma H1299 Cells through Caspase-3-Independent Pathway. 2021, International Journal of Molecular Science, 22, 2006, *Corresponding author

Chul‐Hong Kim, Mi Jin Kim, Jinhong Park, Jinho Kim, Ji‐Young Kim, Mi‐Jin An, Geun‐Seup Shin, Hyun‐Min Lee, Jung‐Woong Kim*. Bisphenol A Exposure Changes the Transcriptomic and Proteomic Dynamics of Human Retinoblastoma Y79 Cells. 2021, Genes, 12, 264, *Corresponding author

Mi-Jin An, Geun-Seup Shin, Hyun-Min Lee, Jung-Woong Kim*. Ablation of SMUG1 Reduces Cell Viability and Increases UVC-Mediated Apoptosis in Hepatocarcinoma HepG2 Cells. 2021, Genes, 12, 201, *Corresponding author

Ji‑Young Kim, Mi Jin Kim, Mi‑Jin An, Geun‑Seup Shin, Hyun‑Min Lee, Chul‑Hong Kim, Jung‑Woong Kim*. Methylparaben induces cell‑cycle arrest and caspase‑3‑mediated apoptosis in human placental BeWo cells. 2020, Molecular & Cellular Toxicology, 16, 409-418, *Corresponding author

Mi Jin Kim, Chul‑Hong Kim, Mi‑Jin An, Geun‑Seup Shin, Hyun‑Min Lee, Ji‑Young Kim, Jae Yoon Hwang, Ju‑Hyun Lee, Jung‑Woong Kim*. Exposure to mercury induced early apoptotic signals in human placental BeWo cells through alteration of cell cycle regulation. 2020, Molecular & Cellular Toxicology, 16, 419-429, *Corresponding author

Mi Jin Kim, Chul-Hong Kim, Mi-Jin An, Ju-Hyun Lee, Geun-Seup Shin, Mina Song and Jung-Woong Kim*. Ethylparaben induces apoptotic cell death in human placenta BeWo cells via the Caspase-3 pathway. 2020, Animal Cells and systems, 24, 34-43, *Corresponding author

Ja Young Hahm, Jin Woo Park, Joo-Young Kang, Junyoung Park, Chul-Hong Kim, Ji-Young Kim, Nam-Chul Ha, Jung-Woong Kim, and Sang-Beom Seo. Acetylation of UHRF1 Regulates Hemi-methylated DNA Binding and Maintenance of Genome-wide DNA Methylation. 2020, Cell Reports, 32, 107958

Mi Jin Kim, Chul Hong Kim, Young Jin Seo, Mi Jin An, Ju Hyun Lee, Geun Seup Shin, Jae Yoon Hwang, Jinhong Park, Ji Young Kim, Seung Yong Hwang, Sangmyung Rhee, Jung Woong Kim*. Transcriptome dynamics of alternative splicing events revealed early phase of apoptosis induced by methylparaben in H1299 human lung carcinoma cells. 2020, Archives of Toxicology, 94, 127-140, *Corresponding author

Hyun-Hee Ryu, TaeHyun Kim, Jung-Woong Kim*, Minkyung Kang, Pojeong Park, Yong Gyu Kim, Hyopil Kim, Jiyeon Ha, Ja Eun Choi, Jisu Lee, Chae-Seok Lim, Chul-Hong Kim, Sang Jeong Kim, Alcino J. Silva, Bong-Kiun Kaang, Yong-Seok Lee. Excitatory neuron–specific SHP2-ERK signaling network regulates synaptic plasticity and memory. 2019, Science Signaling, 12, 1-13, *Co-first author, cover image

Mi-Jin An, Dae-Hyun Kim, Chul-Hong Kim, Mijin Kim, Sangmyung Rhee, Sang-Beom Seo, Jung-Woong Kim*. Histone demethylase KDM3B regulates the transcriptional network of cell-cycle genes in hepatocarcinoma HepG2 cells. 2019, Biochem. Biophys. Res. Commun., 508, 576-582, *Corresponding author

Seobin Yoon, Eui-Hwan Choi, Jung-Woong Kim, Keun P. Kim. Structured illumination microscopy imaging reveals localization of replication protein A between chromosome lateral elements during mammalian meiosis. 2018, Experimental & Molecular Medicine, 50(112), 1-12.

Hyeonsoo Jung, Ji-Young Kim, Kee-Beom Kim, Yun-Cheol Chae, Yoonsoo Hahn, Jung-Woong Kim, Sang-Beom Seo. Deacetylase activity-independent transcriptional activation by HDAC2 during TPA-induced HL-60 cell differentiation. 2018, PLOS One, 1-15.

Mi-Jin An, Chul-Hong Kim, Gyu-You Nam, Dae-Hyun Kim, Sangmyung Rhee, Sung-Jin Cho*, Jung-Woong Kim*. Transcriptome analysis for UVB-induced phototoxicity in mouse retina. 2018, Env. Toxicology, 33, 52-62, *Co-corresponding author

Brenda Irene Medina Jiménez1, Hee-Jin Kwak1, Jong-Seok Park, Jung-Woong Kim* and Sung-Jin Cho*. Developmental biology and potential use of Alboglossiphonia lata (Annelida: Hirudinea) as an “Evo-Devo” model organism. 2017, Frontiers in Zoology, 14(60), 1-12, *Co-corresponding author

Lina Zelinger, Gokhan Karakulah, Vijender Chaitankar, Jung-Woong Kim, Hyun-Jin Yang, Matthew J. Brooks, and Anand Swaroop. Regulation of Noncoding Transcriptome in Developing Photoreceptors by Rod Differentiation Factor NRL. 2017, Invest. Ophthalmol. Vis. Sci., 58, 4422-4435.

Wenhan Yu, Suddhasil Mookherjee, Vijender Chaitankar, Suja Hiriyanna, Jung-Woong Kim, Matthew Brooks, Yasaman Ataeijannati, Xun Sun, Lijin Dong, Tiansen Li, Anand Swaroop, and Zhijian Wu. Nrl knockdown by AAV-delivered CRISPR/Cas9 prevents retinal degeneration in mice. 2017, Nat. Comm., 8:14716, 1-15.

Colin L. Sweeney, Jizhong Zou, Uimook Choi, Randall K. Merling, Alexander Liu, Aaron Bodansky,  Sandra Burkett, Jung-Woong Kim, Suk See De Ravin, and Harry L. Malech. Targeted Repair of CYBB in X-CGD iPSCs Requires Retention of Intronic Sequences for Expression and Functional Correction. 2017, Mol Therapy, 25(2), 321-330.

Chung-Hong Kim, Mi-Jin An, Dae-Hyun Kim, Jung-Woong Kim*. Histone deacetylase 1 (HDAC1) regulates retinal development through a PAX6-dependent pathway. 2017, Biochem. Biophys. Res. Commun., 482(4), 735-741, *Corresponding author

Jung-Woong Kim*, Hyun-Jin Yang*, Matthew John Brooks*, Lina Zelinger, Gökhan Karakülah, Norimoto Gotoh, Alexis Boleda, Linn Gieser, Felipe Giuste, Dustin Thad Whitaker, Ashley Walton, Rafael Villasmil, Jennifer J. Barb, Peter J. Munson, Koray Dogan Kaya, Vijender Chaitankar, Tiziana Cogliati, Anand Swaroop. NRL-mediated Temporal Transcriptome Dynamics Underlies Rod Photoreceptor Morphogenesis and Functional Maturation. 2016, Cell Reports, 17, 2460-2473. *co-first, Selected as a cover image

Jung-Woong Kim*, Hyun-Jin Yang*, Adam Phillip Oel*, Matthew John Brooks, Li Jia, David Charles Plachetzki, Wei Li, William Ted Allison, Anand Swaroop. Recruitment of Rod Photoreceptors from Short Wave length-Sensitive Cones during the Evolution of Nocturnal Vision in Mammals. 2016, Developmental Cell, 37, 520-532. *co-first

Sang-Min Jang*, Jung-Woong Kim*, Chul-Hong Kim, Joo-Hee An, Andrew Johnson, Peter I. Song, Sangmyung Rhee, Kyung-Hee Choi. KAT5-mediated SOX4 acetylation orchestrates chromatin remodeling during myoblast differentiation. 2015, Cell Death and Disease, Aug 20, e1857, *Co-first

Sang-Min Jang, Joo-Hee An, Chul-Hong Kim, Jung-Woong Kim*, Kyung-Hee Choi*. Transcription factor FOXA2-centered transcriptional regulation network in non-small cell lung cancer. 2015, Biochem. Biophys. Res. Commun., June 18, ePub, *Co-corresponding author

Sang-Min Jang, Chul-Hong Kim, Jung-Woong Kim*, Kyung-Hee Choi*. Transcriptional regulatory network of SOX4 during myoblast differentiation. 2015, Biochem. Biophys. Res. Commun., 462(4), 365-370, *Co-corresponding author

Hyun-Jin Yang, Rinki Ratnapriya, Tiziana Cogliati, Jung-Woong Kim, Anand Swaroop. Vision from the next generation sequencing: Multi-dimensional genome-wide analysis of retinal development, aging and disease. 2015, Prog. Ret. Eye Res. Review. 46, 1-30.

Chul-Hong Kim*, Jung-Woong Kim*, Sang-Min Jang, Joo-Hee An, Sang-Beom Seo, Kyung-Hee Choi. The chromodomain-containing histone acetyltransferase TIP60 acts as a code reader, recognizing the epigenetic codes for initiating transcription. 2015, Biosci Biotechnol Biochem., 1-7, *Co-first